MUC1 (Mucin 1)
MUC1 (Mucin 1)
- Used for: Breast cancer, ovarian cancer, pancreatic cancer.
- Why it’s good: Overexpression of MUC1 is seen in many cancers, making it a broad biomarker.
- Limitation: It can be elevated in non-cancerous conditions as well.
The Thomsen–Friedenreich (TF) antigen, also known as CD176, is a disaccharide structure comprising galactose and N-acetylgalactosamine (Galβ1-3GalNAcα1-Ser/Thr). It serves as the core 1 structure in O-linked glycosylation of proteins. In healthy tissues, the TF antigen is typically masked by additional carbohydrate chains or sialylation, rendering it inaccessible to the immune system. However, in many cancer…
EGFR (Epidermal Growth Factor Receptor)
Alpha-Fetoprotein (AFP) is a well-established cancer biomarker with diverse clinical applications, especially in liver and germ cell tumors. Here’s a detailed summary of its biological role, diagnostic value, prognostic utility, and emerging therapeutic applications, based on recent studies: 🔬 What is AFP? AFP is a glycoprotein produced by the fetal liver and yolk sac. After…
TP53 (Tumor Protein p53)
HER2/neu (Human Epidermal Growth Factor Receptor 2)
Circulating Tumor DNA (ctDNA)